A study in Japan found that women were significantly more likely than men to develop rash-like side effects after a first dose of Moderna Inc’s COVID-19 vaccine.
The study of 5,893 participants between May and November last year showed that 22.4 per cent of women developed delayed skin reactions after the first shot, compared to 5.1 per cent of men.
The symptoms were mild and not considered a contraindication of the mRNA-based vaccine, according to the 1st June report in JAMA Dermatology.
Delayed skin reactions, happening on or after six days from the shot, have been also reported as a rare adverse event in the US and Europe, according to the authors from Tokyo’s Self-Defense Forces Central Hospital.
But the incidences appear to be higher in Japan, they wrote, perhaps because of a higher awareness of such symptoms in the country. The greater likelihood among women may be due to differences in weight as well as hormonal and environmental factors, they said.
Moderna representatives in the US and Japan did not immediately respond to a request for comment.
Edits by EP News Bureau