Waters Corporation has launched Xevo TQ-XS mass spectrometer. Enabled by the newly designed StepWave XS ion guide, this mass spectrometry system features a unique combination of ion optics, detection and ionisation technologies resulting in levels of sensitivity not previously seen. The Xevo TQ-XS is expected to be available for shipment in June 2016 and will be on public display for the first time at MSSJ in Osaka, Japan and at ASMS in San Antonio, TX, June 5 – 9.
The new StepWave XS ion guide removes neutral species and transmits ions in a more focused beam to the detector by incorporating segmented quadrupole transfer optics in the second stage. The result is a 2x to 10x increase in signal/ noise over its StepWave predecessor, and it delivers excellent robustness over thousands of injections. The refined design allows the system to quantify challenging compounds at trace levels – even if they are labile or show poor transmission efficiency.
Customer experience has been improved through the introduction of the new tool-free atmospheric pressure ionisation probes. These allow scientists to perform routine maintenance in less than two minutes meaning greater operator-to-operator reproducibility and more time analysing samples.
The Xevo TQ-XS also incorporates the XDR Detector. First introduced on the Xevo TQ-S micro, it is a photomultiplier detection system capable of quantifying sample compounds across a concentration range of six orders of magnitude. Scientists no longer need to dilute and re-inject samples in order to stay within the limited dynamic range of the instrument they have been using.
UniSpray, a novel, proprietary ionisation source available on the Xevo TQ-XS, enables ionisation of a wider range of analytes in a single chromatographic run. The result is an increased response across a wide range of compound polarities for a broader range of compounds accompanied by a boost in signal/ noise, making it possible to consolidate several analytical methods into one, or eliminate the need to change ionisation sources between analyses, saving time and increasing laboratory efficiency.
The Xevo TQ-XS system joins a portfolio of Xevo mass spectrometers including; the Xevo TQD, the Xevo TQ-S micro and the Xevo G2-XS QTof. Xevo mass spectrometers are characterised by their universal ion source architecture: interchangeable ion sources that can be fitted to, or removed from, the face of the mass spectrometer in minutes, without the need to vent the system. This has changed the way analytical chemists with little previous mass spectrometry experience working in high-throughput labs can use the instrumentation at maximum performance.
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