Phenomenex adds two phases to Lux Chiral Bulk Media Line for preparative chromatography

Phenomenex has announced the extension of its successful Lux chiral bulk media line to meet the needs of preparative chromatography applications. Lux Cellulose-3 and Cellulose-4, unique and complementary chiral stationary phases, are now available in a 10 µm particle size for preparative and batch chromatography applications. These two new phases join the existing purification media options of Cellulose-1 and Cellulose-2, providing a dependable, high-resolution screening set with a wide range of selectivity.

The new 10 µm particles are specifically designed for batch chromatography, and columns packed with these particles deliver increased efficiencies over 20 µm particles, enabling the use of shorter columns. This saves both time and money by reducing solvent consumption. The Phenomenex Lux 20 µm particles are still a good choice for customers using simulated moving bed (SMB) technology.

The four 10 µm Lux Cellulose chiral phases benefit from Phenomenex’s unique manufacturing process and silica coating technology. Lux Cellulose-1 uses cellulose tris (3, 5-dimethylphenylcarbamate) as the chiral selector. Lux Cellulose-2 provides a second chiral selector, cellulose tris (3-chloro-4-methylphenylcarbamate) providing a unique chlorinated stationary phase with chiral recognition abilities that complement the Lux family of columns. Lux Cellulose-3 utilises Cellulose tris (4-methylbenzoate) as the chiral selector, a variant cellulose ester derivative that offers unique chiral recognition abilities to provide enantioseparation when other phases fail. Lux Cellulose-4 incorporates Cellulose tris (4-chloro-3-methylphenylcarbamate) as the chiral selector – a chlorinated cellulose phenylcarbamate derivative that offers unique chiral recognition abilities.

“The successful resolution of chiral compounds requires more than one stationary phase and the more phases you have to choose from, the better your chances of resolving enantiomers,” explains Marc Jacob, Product Manager, Phenomenex.” Phenomenex also offers several free tools for chiral chromatography. On the Phenomenex website, users are able to use the online chiral application search to quickly and easily search over 2,000 chiral applications by drawing the compound structure or by searching the application name.

EP News Bureau – Mumbai